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Second, zinc and melatonin synthesis overlap: zinc is a cofactor in serotonin-to-melatonin conversion

In 2021, Kishimoto et al., in a double-blind, placebo-controlled clinical trial, evaluated the anti-inflammatory effects of curcuRouge for 4 weeks on systemic inflammation in adults over 60 years of age in Japan [62]

FIGURE 6 Oxidative stress and inflammation are considered fundamental mediators of chronic obstructive pulmonary disease (COPD) pathophysiology (Figure 6)